NTRK3 Antikörper (Internal Region)

Produktnummer ABIN2855417

Produktdetails anti-NTRK3 Antikörper

Target: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NTRK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Rhesusaffen

Kreuzreaktivität (Details): Rhesus Monkey (100 %)

Produktmerkmale: Rabbit polyclonal antibody to TrkC (neurotrophic tyrosine kinase, receptor, type 3)
TrkC antibody [N2C1], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TrkC. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3 , Molt-4 , Raji , NIH-3T3

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NTRK3

Target: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Andere Bezeichnung: TrkC (NTRK3 Produkte)

Synonyme: TRKC antikoerper, gp145(trkC) antikoerper, trkC antikoerper, AW125844 antikoerper, Ntrk3_tv3 antikoerper, TrkC antikoerper, neurotrophic receptor tyrosine kinase 3 antikoerper, neurotrophic tyrosine kinase, receptor, type 3 antikoerper, NTRK3 antikoerper, Ntrk3 antikoerper

Hintergrund: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht: 94 kDa

Gen-ID: 4916

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, Regulation of Cell Size