BMPR1B Antikörper

Produktnummer ABIN2855400

Produktdetails anti-BMPR1B Antikörper

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMPR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Produktmerkmale: Rabbit polyclonal antibody to BMPR1B (bone morphogenetic protein receptor, type IB)
BMPR1B antibody [N3C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human BMPR1B. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2 , human BMPR1B-transfected 293T cells , Neuro2A , C8D30 , NIH-3T3 , Rat2

Validation: Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-BMPR1B Antikörper (ABIN2855400)

Chung, Gao, Jegga, Das: "Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a." in: Molecular and cellular endocrinology, Vol. 400, pp. 48-60, (2015) (PubMed).

Details zu BMPR1B

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Andere Bezeichnung: bone morphogenetic protein receptor type 1B (BMPR1B Produkte)

Synonyme: ALK6 antikoerper, BMPR-IB antikoerper, FecB antikoerper, alk-6 antikoerper, alk6 antikoerper, cdw293 antikoerper, alk6b antikoerper, zgc:172219 antikoerper, BMPR1B antikoerper, AI385617 antikoerper, ALK-6 antikoerper, AV355320 antikoerper, Acvrlk6 antikoerper, Alk6 antikoerper, BMPR-1B antikoerper, CFK-43a antikoerper, SKR6 antikoerper, BR1b antikoerper, alk6tr antikoerper, bmpr1b antikoerper, zALK-6 antikoerper, zgc:92220 antikoerper, CDw293 antikoerper, BMP15 antikoerper, BMPRIB antikoerper, RPK-1 antikoerper, bone morphogenetic protein receptor type 1B antikoerper, bone morphogenetic protein receptor, type IBb antikoerper, bone morphogenetic protein receptor, type 1B antikoerper, bone morphogenetic protein receptor, type IBa antikoerper, BMPR1B antikoerper, bmpr1b antikoerper, bmpr1bb antikoerper, Bmpr1b antikoerper, bmpr1ba antikoerper

Hintergrund: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

Cellular Localization: Membrane

Molekulargewicht: 57 kDa

Gen-ID: 658

UniProt: O00238