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alpha Adducin Antikörper

ADD1 Reaktivität: Human WB, IF, IHC (p), ICC, IHC (wm) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855099
  • Target Alle alpha Adducin (ADD1) Antikörper anzeigen
    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
    Reaktivität
    • 92
    • 56
    • 55
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 91
    • 2
    Kaninchen
    Klonalität
    • 90
    • 2
    Polyklonal
    Konjugat
    • 58
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser alpha Adducin Antikörper ist unkonjugiert
    Applikation
    • 60
    • 36
    • 32
    • 28
    • 28
    • 26
    • 21
    • 16
    • 11
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm))
    Kreuzreaktivität
    Human, Maus, Zebrafisch (Danio rerio)
    Produktmerkmale
    Rabbit Polyclonal antibody to alpha Adducin (adducin 1 (alpha))
    alpha Adducin antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human alpha Adducin. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product ADD1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Jurkat

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.02 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
    Andere Bezeichnung
    adducin 1 (ADD1 Produkte)
    Synonyme
    ADDA antikoerper, AI256389 antikoerper, alpha-adducin antikoerper, bZ1H20.1 antikoerper, cb787 antikoerper, zgc:158352 antikoerper, add2 antikoerper, adda antikoerper, add1-a antikoerper, ADD1 antikoerper, adducin 1 antikoerper, adducin 1 (alpha) antikoerper, adducin 1 S homeolog antikoerper, ADD1 antikoerper, Add1 antikoerper, add1 antikoerper, add1.S antikoerper
    Hintergrund
    Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.

    Cellular Localization: Cytoplasm , cytoskeleton , Cell membrane
    Molekulargewicht
    81 kDa
    Gen-ID
    118
    UniProt
    P35611
    Pathways
    Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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