MMP 9 Antikörper

Produktnummer ABIN2854757

Produktdetails anti-MMP 9 Antikörper

Target: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Whole Mount) (IHC (wm))

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to MMP9 (matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase))
MMP9 antibody [N2C1], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MMP9. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.88 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-MMP 9 Antikörper (ABIN2854757)

Tsai, Kuo, Lin, Ho, Wang, Chuang, Liou: "Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population." in: Cells, Vol. 9, Issue 8, (2020) (PubMed).

Chung, Lin, Lin, Chan, Yang: "Antitumor effect of kurarinone and underlying mechanism in small cell lung carcinoma cells." in: OncoTargets and therapy, Vol. 12, pp. 6119-6131, (2019) (PubMed).

Lopez-Charcas, Espinosa, Alfaro, Herrera-Carrillo, Ramirez-Cordero, Cortes-Reynosa, Perez Salazar, Berumen, Gomora: "The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity." in: Scientific reports, Vol. 8, Issue 1, pp. 12995, (2019) (PubMed).

Kim, Choi, Lee, Soh, Kim, Park: "Senescent tumor cells lead the collective invasion in thyroid cancer." in: Nature communications, Vol. 8, pp. 15208, (2018) (PubMed).

Gao, Zhao, Zhang, Lu, Liu, Geng, Huang, Zhang, Lu: "The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1." in: Scientific reports, Vol. 6, pp. 19874, (2016) (PubMed).

Details zu MMP 9

Target: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Andere Bezeichnung: matrix metallopeptidase 9 (MMP9 Produkte)

Synonyme: CLG4B antikoerper, GELB antikoerper, MANDP2 antikoerper, MMP-9 antikoerper, AW743869 antikoerper, B/MMP9 antikoerper, Clg4b antikoerper, pro-MMP-9 antikoerper, mmp-9 antikoerper, fgMMP-9 antikoerper, mmp9 antikoerper, ZFMMP-9 antikoerper, wu:fb02g06 antikoerper, wu:fb07b05 antikoerper, wu:fi98c09 antikoerper, wu:fj05a08 antikoerper, zgc:64165 antikoerper, clg4b antikoerper, gelb antikoerper, mandp2 antikoerper, matrix metallopeptidase 9 antikoerper, collagenase antikoerper, matrix metalloproteinase 9 antikoerper, matrix metallopeptidase 9 S homeolog antikoerper, MMP9 antikoerper, RB3913 antikoerper, BPSS0666 antikoerper, Sbal_3732 antikoerper, Bcer98_0486 antikoerper, Shew185_0630 antikoerper, Shal_3056 antikoerper, Sbal195_0657 antikoerper, Lbys_3550 antikoerper, Palpr_2084 antikoerper, Mmp9 antikoerper, mmp9 antikoerper, mmp9.S antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Cellular Localization: Secreted , extracellular space , extracellular matrix

Molekulargewicht: 78 kDa

Gen-ID: 4318

UniProt: P14780

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events