CLP1 Antikörper (AA 1-100) (Alexa Fluor 594)

Produktnummer ABIN2814236

Produktdetails anti-CLP1 Antikörper (Alexa Fluor 594)

Target: CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLP1 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HEAB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CLP1

Target: CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))

Andere Bezeichnung: HEAB (CLP1 Produkte)

Synonyme: Heab antikoerper, RGD1307679 antikoerper, AI462438 antikoerper, ACDP1 antikoerper, CLP-1 antikoerper, CGP-39 antikoerper, GP-39 antikoerper, SPC-40 antikoerper, SPS-40 antikoerper, YKL-40 antikoerper, HEAB antikoerper, hClp1 antikoerper, fa28a12 antikoerper, wu:fa28a12 antikoerper, clp1 antikoerper, cleavage and polyadenylation factor I subunit 1 antikoerper, CLP1, cleavage and polyadenylation factor I subunit antikoerper, cyclin and CBS domain divalent metal cation transport mediator 1 antikoerper, chitinase 3-like 1 (cartilage glycoprotein-39) antikoerper, cleavage and polyadenylation factor I subunit 1 L homeolog antikoerper, Clp1 antikoerper, CNNM1 antikoerper, CHI3L1 antikoerper, CLP1 antikoerper, clp1 antikoerper, clp1.L antikoerper

Hintergrund:

Synonyms: ATP/GTP binding protein, CLP 1, clp1, CLP1 cleavage and polyadenylation factor I subunit homolog, CLP1, cleavage and polyadenylation factor I subunit, homolog S. cerevisiae, CLP1, yeast, homolog of, CLP1_HUMAN, hClp1, Homolog of yeast CFIA subunit Clp1p, Polynucleotide kinase Clp1, Pre mRNA cleavage complex II protein Clp1, Pre-mRNA cleavage complex II protein Clp1.

Background: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilizing magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D, mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.

Gen-ID: 10978

Pathways: Ribonucleoprotein Complex Subunit Organization