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GRB14 Antikörper (AA 221-320) (Alexa Fluor 594)

GRB14 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2814024
  • Target Alle GRB14 Antikörper anzeigen
    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
    Bindungsspezifität
    • 14
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-320
    Reaktivität
    • 30
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 30
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GRB14 Antikörper ist konjugiert mit Alexa Fluor 594
    Applikation
    • 12
    • 12
    • 12
    • 11
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Spezifität
    This antibody may also detect the similar protein GRB10 due to an 83 % sequence similarity in the immunogen sequence.
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GRB 14
    Isotyp
    IgG
    Top Product
    Discover our top product GRB14 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
    Andere Bezeichnung
    GRB 14 (GRB14 Produkte)
    Synonyme
    GRB14 antikoerper, AI505286 antikoerper, growth factor receptor bound protein 14 antikoerper, GRB14 antikoerper, grb14 antikoerper, Grb14 antikoerper
    Hintergrund

    Synonyms: Growth factor receptor-bound protein 14, GRB14 adapter protein, GRB14

    Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

    Gen-ID
    2888
    UniProt
    Q14449
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