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FBXL21 Antikörper (AA 121-220) (Alexa Fluor 594)

FBXL21 Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2813153
  • Target Alle FBXL21 Antikörper anzeigen
    FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))
    Bindungsspezifität
    • 14
    • 6
    • 2
    • 1
    • 1
    AA 121-220
    Reaktivität
    • 15
    • 11
    Maus
    Wirt
    • 22
    • 3
    Kaninchen
    Klonalität
    • 22
    • 2
    Polyklonal
    Konjugat
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FBXL21 Antikörper ist konjugiert mit Alexa Fluor 594
    Applikation
    • 21
    • 13
    • 12
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FBXL21/FBL3B
    Isotyp
    IgG
    Top Product
    Discover our top product FBXL21 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))
    Andere Bezeichnung
    FBXL21 (FBXL21 Produkte)
    Synonyme
    D630045D17Rik antikoerper, FBL3B antikoerper, FBXL3B antikoerper, Psttm antikoerper, FBXL3P antikoerper, Fbl21 antikoerper, F-box and leucine rich repeat protein 21 antikoerper, F-box and leucine-rich repeat protein 21 antikoerper, F-box and leucine rich repeat protein 21 (gene/pseudogene) antikoerper, FBXL21 antikoerper, Fbxl21 antikoerper
    Hintergrund

    Synonyms: F box and leucine rich repeat protein 21, F box and leucine rich repeat protein 3 pseudogene, F box and leucine rich repeat protein 3B, F box protein Fbl3b, F box/LRR repeat protein 21, F box/LRR repeat protein 3B, Fbl 21, FBXL 21, FBXL-21, FBL 3, FBL 3B, Fbl21, FBL3, FBL-3B, FBL 3B, FBL3B, FBXL 21, FBXL 3B, FBXL 3P, FBXL3B, FBXL3P, MGC120237, FXL21_HUMAN.

    Background: FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.

    Gen-ID
    26223
    Pathways
    Photoperiodism
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