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EMP1 Antikörper (AA 101-160) (Alexa Fluor 594)

EMP1 Reaktivität: Human, Maus, Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2812776
  • Target Alle EMP1 Produkte
    EMP1 (Epithelial Membrane Protein 1 (EMP1))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 101-160
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 33
    • 1
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EMP1 Antikörper ist konjugiert mit Alexa Fluor 594
    Applikation
    • 19
    • 15
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Emp1
    Isotyp
    IgG
  • Applikationshinweise
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    EMP1 (Epithelial Membrane Protein 1 (EMP1))
    Andere Bezeichnung
    EMP1 (EMP1 Produkte)
    Synonyme
    MGC84779 antikoerper, EMP1 antikoerper, si:ch73-90k17.2 antikoerper, CL-20 antikoerper, EMP-1 antikoerper, TMP antikoerper, I-8-09 antikoerper, ENP1MR antikoerper, epithelial membrane protein 1 antikoerper, epithelial membrane protein 1 L homeolog antikoerper, EMP1 antikoerper, emp1.L antikoerper, emp1 antikoerper, Emp1 antikoerper
    Hintergrund

    Synonyms: TMP, I-8-9, Epithelial membrane protein 1, EMP-1, Tumor-associated membrane protein, Emp1

    Background: Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.

    Gen-ID
    13730
    UniProt
    P47801
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