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CLEC7A Antikörper (AA 66-110) (Alexa Fluor 594)

CLEC7A Reaktivität: Human, Maus FACS, WB Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2812309
  • Target Alle CLEC7A Antikörper anzeigen
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Bindungsspezifität
    • 14
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-110
    Reaktivität
    • 58
    • 37
    • 6
    • 1
    Human, Maus
    Wirt
    • 40
    • 19
    • 19
    Kaninchen
    Klonalität
    • 41
    • 32
    Polyklonal
    Konjugat
    • 27
    • 11
    • 11
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLEC7A Antikörper ist konjugiert mit Alexa Fluor 594
    Applikation
    • 43
    • 38
    • 25
    • 23
    • 9
    • 8
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Beta-glucan receptor
    Isotyp
    IgG
    Top Product
    Discover our top product CLEC7A Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Andere Bezeichnung
    DECTIN-1/ beta Glucan Receptor (CLEC7A Produkte)
    Synonyme
    CLEC7A antikoerper, BGR antikoerper, Clecsf12 antikoerper, beta-GR antikoerper, CANDF4 antikoerper, CLECSF12 antikoerper, DECTIN1 antikoerper, Clec7b antikoerper, RGD1565140 antikoerper, C-type lectin domain containing 7A antikoerper, C-type lectin domain family 7, member a antikoerper, CLEC7A antikoerper, Clec7a antikoerper
    Hintergrund

    Synonyms: BGR, CD369, CANDF4, DECTIN1, CLECSF12, C-type lectin domain family 7 member A, Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CLEC7A, UNQ539/PRO1082

    Background: Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).

    Gen-ID
    64581
    UniProt
    Q9BXN2
    Pathways
    Activation of Innate immune Response
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