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CDX1 Antikörper (Alexa Fluor 594)

CDX1 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2811517
  • Target Alle CDX1 Antikörper anzeigen
    CDX1 (Caudal Type Homeobox 1 (CDX1))
    Reaktivität
    • 60
    • 26
    • 19
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 53
    • 8
    Kaninchen
    Klonalität
    • 43
    • 18
    Polyklonal
    Konjugat
    • 29
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDX1 Antikörper ist konjugiert mit Alexa Fluor 594
    Applikation
    • 46
    • 21
    • 14
    • 12
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDX1
    Isotyp
    IgG
    Top Product
    Discover our top product CDX1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CDX1 (Caudal Type Homeobox 1 (CDX1))
    Andere Bezeichnung
    CDX1 (CDX1 Produkte)
    Synonyme
    Cdx antikoerper, Cdx-1 antikoerper, cdx-1 antikoerper, xcad2 antikoerper, xtcad2 antikoerper, CDX-A antikoerper, CDXA antikoerper, CHOX-CAD1 antikoerper, CHox-cad antikoerper, CDX1 antikoerper, xCAD2 antikoerper, zgc:165581 antikoerper, cdx2 antikoerper, caudal type homeobox 1 antikoerper, caudal type homeo box 1 antikoerper, caudal type homeobox 1 S homeolog antikoerper, caudal type homeobox 1 b antikoerper, caudal type homeobox 1a antikoerper, CDX1 antikoerper, Cdx1 antikoerper, cdx1 antikoerper, cdx1.S antikoerper, cdx1b antikoerper, cdx1a antikoerper
    Hintergrund

    Synonyms: Caudal type homeo box transcription factor 1, Caudal type homeobox 1, Caudal type homeobox protein, Caudal type homeobox protein CDX1, Caudal type homeobox transcription factor 1, Caudal-type homeobox protein 1, CDX1, CDX1_HUMAN, Homeobox protein CDX 1, Homeobox protein CDX-1.

    Background: The members of the murine Cdx family (Cdx1, Cdx2, and Cdx4) are members of the caudal-type homeobox family of genes, which are homologues of the Drosophila caudal? gene required for anterior-posterior regional identity. The intestine-specific transcription factors Cdx1 and Cdx2 are candidate genes for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. The relative expression of Cdx1 to Cdx2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Expression of the Cdx1 homeobox gene in epithelial intestinal cells promotes cellular growth and differentiation. Cdx1 positively regulates its own expression. Cdx1 and Cdx2 are expressed in the small intestine and colon of fetus and adult. A decrease in human Cdx1 and/or Cdx2 expression is associated with colorectal tumorigenesis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways. The human Cdx1 gene maps to chromosome 5q31-q33 and encodes a 265-amino acid protein.

    Gen-ID
    1044
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