MKLN1 Antikörper (AA 301-400) (Alexa Fluor 594)

Produktnummer ABIN2804206

Produktdetails anti-MKLN1 Antikörper (Alexa Fluor 594)

Target: MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))

Bindungsspezifität: AA 301-400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MKLN1 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MKLN1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MKLN1

Target: MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))

Andere Bezeichnung: MKLN1 (MKLN1 Produkte)

Synonyme: fc60a07 antikoerper, wu:fc60a07 antikoerper, mkln1 antikoerper, MGC81665 antikoerper, MKLN1 antikoerper, MGC139211 antikoerper, TWA2 antikoerper, A130067F06Rik antikoerper, AU015903 antikoerper, BB154892 antikoerper, Muskelin antikoerper, DKFZp468G1027 antikoerper, muskelin 1, intracellular mediator containing kelch motifs antikoerper, muskelin 1 antikoerper, muskelin 1 L homeolog antikoerper, mkln1 antikoerper, MKLN1 antikoerper, mkln1.L antikoerper, Mkln1 antikoerper

Hintergrund:

Synonyms: MKLN 1, Mkln1, MKLN1_HUMAN, muskelin 1, intracellular mediator containing kelch mots, Muskelin.

Background: Muskelin is a 735 amino acid nuclear and cytoplasmic protein that mediates cytoskeletal responses and cell spreading to Thrombospondin 1, an extracellular matrix glycoprotein. Forming a CTLH complex with RMND5A, Ran BP-M and TWA1, Muskelin exists as two alternatively spliced isoforms. Muskelin is implicated as an isoform-specific anchoring protein for the prostaglandin EP3 receptor, and contains one LisH domain, a CTLH domain, six Kelch repeats and an N-terminal discoidin-like domain through which it self-associates via a head-to-tail mechanism. Human and mouse Muskelin share 98 % amino acid seqeuence homology and are encoded by genes located on chromosomes 7q32.3 and 6 A3.3, respectively.