STRADA Antikörper (AA 1-100) (Alexa Fluor 594)

Produktnummer ABIN2803890

Produktdetails anti-STRADA Antikörper (Alexa Fluor 594)

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Bindungsspezifität: AA 1-100

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADA Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LYK5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu STRADA

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Andere Bezeichnung: LYK5 (STRADA Produkte)

Synonyme: fj99g05 antikoerper, zgc:56109 antikoerper, wu:fj99g05 antikoerper, lyk5 antikoerper, LYK5 antikoerper, NY-BR-96 antikoerper, PMSE antikoerper, STRAD antikoerper, Stlk antikoerper, Lyk5 antikoerper, 2610019A05Rik antikoerper, 6030402H20Rik antikoerper, AI480680 antikoerper, E130112C09Rik antikoerper, STE20-related kinase adaptor alpha antikoerper, ste20-related kinase adaptor alpha antikoerper, STRADA antikoerper, strada antikoerper, Strada antikoerper

Hintergrund:

Synonyms: Serologically defined breast cancer antigen NY BR 96, STRAD alpha, Protein kinase LYK5, STE20 related adapter protein, STRAD, STRAA_HUMAN.

Background: Members of the STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.

Gen-ID: 92335

Pathways: AMPK Signaling