LIMS2 Antikörper (AA 251-341) (Alexa Fluor 594)

Produktnummer ABIN2803779

Produktdetails anti-LIMS2 Antikörper (Alexa Fluor 594)

Target: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Bindungsspezifität: AA 251-341

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIMS2 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LIMS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LIMS2

Target: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Andere Bezeichnung: LIMS2 (LIMS2 Produkte)

Synonyme: PINCH2 antikoerper, PINCH-2 antikoerper, LIMS1 antikoerper, LIM and senescent cell antigen like domains 2 antikoerper, LIM zinc finger domain containing 2 antikoerper, Lims2 antikoerper, LIMS2 antikoerper

Hintergrund:

Synonyms: FLJ10044, ILK binding protein, LIM and senescent cell antigen like domains 2, LIM and senescent cell antigen-like-containing domain protein 2, LIM-like protein 2, LIMS2, LIMS2_HUMAN, Particularly interesting new Cys-His protein 2, PINCH 2, PINCH-2, PINCH2.

Background: Pinch is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cytoplasmic protein expressed in most tissues and consists of five LIM domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by another member of the Pinch family, PINCH-2, which also forms a complex with ILK.

Pathways: Cell-Cell Junction Organization