Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Cyclin D2 Antikörper

CCND2 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1944917
  • Target Alle Cyclin D2 (CCND2) Antikörper anzeigen
    Cyclin D2 (CCND2)
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 81
    • 25
    Kaninchen
    Klonalität
    • 84
    • 22
    Polyklonal
    Konjugat
    • 53
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cyclin D2 Antikörper ist unkonjugiert
    Applikation
    • 82
    • 40
    • 24
    • 18
    • 15
    • 13
    • 13
    • 11
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Isotyp
    IgG
    Top Product
    Discover our top product CCND2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Lagerung
    4 °C,-20 °C
  • Palmero, Holder, Sinclair, Dickson, Peters: "Cyclins D1 and D2 are differentially expressed in human B-lymphoid cell lines." in: Oncogene, Vol. 8, Issue 4, pp. 1049-54, (1993) (PubMed).

    Xiong, Menninger, Beach, Ward: "Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins." in: Genomics, Vol. 13, Issue 3, pp. 575-84, (1992) (PubMed).

  • Target
    Cyclin D2 (CCND2)
    Andere Bezeichnung
    Cyclin D2 (CCND2 Produkte)
    Synonyme
    si:ch211-240j22.2 antikoerper, ccnd2 antikoerper, CCND2 antikoerper, kiak0002 antikoerper, zgc:162280 antikoerper, LOC100224096 antikoerper, KIAK0002 antikoerper, BF642806 antikoerper, C86853 antikoerper, Vin-1 antikoerper, Vin1 antikoerper, cD2 antikoerper, 2600016F06Rik antikoerper, AI256817 antikoerper, cyclin D2, b antikoerper, cyclin D2 S homeolog antikoerper, cyclin D2 antikoerper, G1/S-specific cyclin-D2 antikoerper, cyclin D2, a antikoerper, cyclin D2 L homeolog antikoerper, ccnd2b antikoerper, ccnd2.S antikoerper, CCND2 antikoerper, ccnd2 antikoerper, ccnd2a antikoerper, Ccnd2 antikoerper, ccnd2.L antikoerper
    Hintergrund
    Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
    Molekulargewicht
    33067 Da
    Gen-ID
    894
    UniProt
    P30279
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases
Sie sind hier:
Kundenservice