ATP6V0B Antikörper (Center)

Produktnummer ABIN2797005

Produktdetails anti-ATP6V0B Antikörper

Target: ATP6V0B (ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))

Bindungsspezifität: AA 104-131, Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V0B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Rabbit Anti-Human ATP6V0B (Center) Antibody

Immunogen: This ATP6V0B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-131 amino acids from the Central region of human ATP6V0B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50ATP6V0B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu ATP6V0B

Target: ATP6V0B (ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))

Andere Bezeichnung: ATP6V0B (ATP6V0B Produkte)

Synonyme: ATP6F antikoerper, HATPL antikoerper, VMA16 antikoerper, 2310024H13Rik antikoerper, Atp6f antikoerper, ATPase H+ transporting V0 subunit b antikoerper, ATPase, H+ transporting, lysosomal V0 subunit B antikoerper, ATPase H+ transporting V0 subunit B antikoerper, ATP6V0B antikoerper, Atp6v0b antikoerper

Hintergrund:

Target Description: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.

Gene Symbol: ATP6V0B

Molekulargewicht: 21406 Da

Gen-ID: 533

UniProt: Q99437

Pathways: Transition Metal Ion Homeostasis, Proton Transport