PAAF1 Antikörper (N-Term)

Produktnummer ABIN2794640

Produktdetails anti-PAAF1 Antikörper

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Bindungsspezifität: AA 109-138, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Rabbit Anti-Human PAAF1 (N-term) Antibody

Immunogen: This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of PAAF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PAAF1

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Andere Bezeichnung: PAAF1 (PAAF1 Produkte)

Synonyme: paaf antikoerper, rpn14 antikoerper, wdr71 antikoerper, WDR71 antikoerper, MGC146521 antikoerper, PAAF antikoerper, Rpn14 antikoerper, proteasomal ATPase associated factor 1 S homeolog antikoerper, proteasomal ATPase associated factor 1 antikoerper, paaf1.S antikoerper, PAAF1 antikoerper, paaf1 antikoerper, Paaf1 antikoerper

Hintergrund:

Target Description: PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.

Gene Symbol: PAAF1

Molekulargewicht: 42190 Da

Gen-ID: 80227

UniProt: Q9BRP4