TCEB1 Antikörper (Middle Region)
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- Target Alle TCEB1 Antikörper anzeigen
- TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Hund, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TCEB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- AENETNEVNF REIPSHVLSK VCMYFTYKVR YTNSSTEIPE FPIAPEIALE
- Kreuzreaktivität
- Rind (Kuh), Hund, Huhn, Fruchtfliege (Drosophila melanogaster), Human, Maus, Ratte (Rattus)
- Homologie
- Dog: 100%, Human: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TCEB1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TCEB1
- Top Product
- Discover our top product TCEB1 Primärantikörper
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- Applikationshinweise
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WB Suggested Anti-TCEB1 Antibody Titration: 1.0 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Kommentare
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Antigen size: 112 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
- Andere Bezeichnung
- TCEB1 (TCEB1 Produkte)
- Synonyme
- 2610043E24Rik antikoerper, 2610301I15Rik antikoerper, AA407206 antikoerper, AI987979 antikoerper, AW049146 antikoerper, SIII antikoerper, eloC antikoerper, TCEB1 antikoerper, fb09f09 antikoerper, wu:fb09f09 antikoerper, zgc:111990 antikoerper, zgc:92635 antikoerper, elongin C antikoerper, elongin C L homeolog antikoerper, transcription elongation factor B (SIII), polypeptide 1b antikoerper, Eloc antikoerper, eloc.L antikoerper, ELOC antikoerper, tceb1b antikoerper
- Hintergrund
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TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alias Symbols: SIII, eloC
Protein Interaction Partner: UBC, TCEB2, FUS, vif, METTL21C, SOCS4, CUL5, PRAME, POP1, MDM2, VHL, ASB18, ASB12, ASB14, ASB15, ASB9, ASB8, ASB7, ASB5, ASB10, ASB16, ASB13, ASB1, ASB3, APEX1, CUL2, Zswim8, ASB2, CPTP, CBX5, MRAS, JTB, RCAN2, SOCS1, CUL3, WNT7B, NEDD8, HIF1A, EFNB3, CYP
Protein Size: 112 - Molekulargewicht
- 12 kDa
- Gen-ID
- 6921
- NCBI Accession
- NM_005648, NP_005639
- UniProt
- Q15369
- Pathways
- SARS-CoV-2 Protein Interaktom
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