GTF2H1 Antikörper (Middle Region)

Produktnummer ABIN2792659

Produktdetails anti-GTF2H1 Antikörper

Target: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Hund, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ERFQVTKLCP FQEKIRRQYL STNLVSHIEE MLQTAYNKLH TWQSRRLMKK

Kreuzreaktivität: Rind (Kuh), Hund, Huhn, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GTF2H1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GTF2H1

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-GTF2H1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: ACHN cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 548 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GTF2H1

Target: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Andere Bezeichnung: GTF2H1 / BTF2 (GTF2H1 Produkte)

Synonyme: 62kDa antikoerper, AW743425 antikoerper, AW822074 antikoerper, BTF2 p62 antikoerper, C77871 antikoerper, p62 antikoerper, GTF2H1 antikoerper, BTF2 antikoerper, P62 antikoerper, TFB1 antikoerper, TFIIH antikoerper, gtf2h1 antikoerper, MGC53309 antikoerper, btf2 antikoerper, tfiih antikoerper, CG8151 antikoerper, Dmel\\CG8151 antikoerper, Dmp62 antikoerper, TfBl antikoerper, l(2)06949 antikoerper, l(2)06950 antikoerper, zgc:92126 antikoerper, general transcription factor IIH subunit 1 antikoerper, general transcription factor II H, polypeptide 1 antikoerper, general transcription factor IIH subunit 1 L homeolog antikoerper, Transcription factor B1 antikoerper, general transcription factor IIH, polypeptide 1 antikoerper, GTF2H1 antikoerper, Gtf2h1 antikoerper, gtf2h1.L antikoerper, gtf2h1 antikoerper, Tfb1 antikoerper

Hintergrund: GTF2H1 is the component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
Alias Symbols: BTF2, TFIIH, TFB1
Protein Interaction Partner: UBC, CDK7, TP53, RNF11, ERCC5, KLF1, HNF4A, E2F1, TCEA1, POLR2A, GTF2E1, POLR2C, KPNA3, GTF2H2, ACTN1, USHBP1, UVSSA, TRIOBP, TNIP1, REEP5, MMS19, ERCC2, GTF2H4, GTF2H3, ERCC3, RB1, MNAT1, tat, GTF2F1, CTD, RAD23A, XPC, XPA, RPA2, RPA1, RAD23B, ERCC4, ERC
Protein Size: 548

Molekulargewicht: 62 kDa

Gen-ID: 2965

NCBI Accession: NM_005316, NP_005307

UniProt: P32780

Pathways: DNA Reparatur