TFAP2A Antikörper (C-Term)
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- Target Alle TFAP2A Antikörper anzeigen
- TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TFAP2A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- NLISHGFGSP AVCAAVTALQ NYLTEALKAM DKMYLSNNPN SHTDNNAKSS
- Kreuzreaktivität
- Rind (Kuh), Huhn, Human, Maus, Schwein, Ratte (Rattus)
- Homologie
- Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TFAP2A. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human TFAP2A
- Top Product
- Discover our top product TFAP2A Primärantikörper
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- Applikationshinweise
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WB Suggested Anti-TFAP2A Antibody Titration: 1.25 µg/mL
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Kommentare
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Antigen size: 437 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
- Andere Bezeichnung
- AP-2 alpha / TFAP2A (TFAP2A Produkte)
- Synonyme
- TFAP2A antikoerper, Ap-2 antikoerper, AP-2 antikoerper, AP-2alpha antikoerper, AP2TF antikoerper, BOFS antikoerper, TFAP2 antikoerper, ap2 antikoerper, xap2 antikoerper, XAP-2 antikoerper, ap2tf antikoerper, tfap2 antikoerper, ap-2alpha antikoerper, tfap2alpha antikoerper, cb93 antikoerper, fb83f04 antikoerper, fc31a07 antikoerper, wu:fb83f04 antikoerper, wu:fc31a07 antikoerper, tfap2a-a antikoerper, tcfap2a antikoerper, ap2a antikoerper, AP2alpha antikoerper, Ap2 antikoerper, Ap2tf antikoerper, Tcfap2a antikoerper, AP2 antikoerper, transcription factor AP-2 alpha antikoerper, transcription factor AP-2 antikoerper, tto transcription factor AP-2 alpha antikoerper, to transcription factor AP-2 alpha L homeolog antikoerper, to transcription factor AP-2 alpha S homeolog antikoerper, Transcription factor AP-2 alpha antikoerper, transcription factor AP-2, alpha antikoerper, TFAP2A antikoerper, LOC100302602 antikoerper, tfap2a antikoerper, tfap2a.L antikoerper, tfap2a.S antikoerper, ap2a antikoerper, Tfap2a antikoerper
- Hintergrund
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TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM].
Alias Symbols: AP-2, BOFS, AP2TF, TFAP2, AP-2alpha
Protein Interaction Partner: MKRN3, GSTO2, KCTD15, SUMO1, HECW2, SP1, BAG3, RB1, UBC, DAB2, Fcho2, EPAS1, SRA1, EPS15, KCTD1, EPN1, SH3BP4, UBE2I, AURKA, BRCA1, DNMT3A, ELAVL1, SUMO4, SUMO2, NPM1, YY1, PPARG, EPN2, CITED4, LDLRAP1, CITED2, EP300, MAGI1, WWP2, WWP1, HIP1, CASP6, CASP3
Protein Size: 437 - Molekulargewicht
- 48 kDa
- Gen-ID
- 7020
- NCBI Accession
- NM_003220, NP_003211
- UniProt
- P05549
- Pathways
- Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism
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