PAX2A Antikörper (Middle Region)

Produktnummer ABIN2792619

Produktdetails anti-PAX2A Antikörper

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Kaninchen, Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: DPVGSYSING ILGIPRSNGE KRKRDEDVSE GSVPNGDSQS GVDSLRKHLR

Kreuzreaktivität: Human

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PAX2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PAX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 417 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PAX2A

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Andere Bezeichnung: PAX2 (PAX2A Produkte)

Synonyme: PAPRS antikoerper, Opdc antikoerper, Pax-2 antikoerper, Pax-2a antikoerper, XPax-2 antikoerper, XPax2 antikoerper, pax-2 antikoerper, pax2 antikoerper, xPax-2a antikoerper, PAXZF-B antikoerper, cb378 antikoerper, noi antikoerper, pax-b antikoerper, pax2.1 antikoerper, pax2a1 antikoerper, pax[zf-b] antikoerper, paxb antikoerper, pax2.2 antikoerper, paired box 2 antikoerper, paired box 2 L homeolog antikoerper, paired box 2a antikoerper, paired box 2b antikoerper, PAX2 antikoerper, Pax2 antikoerper, pax2.L antikoerper, pax2a antikoerper, pax2b antikoerper

Hintergrund: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: RP11-179B2.1
Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, RB1, BRCA1, SFRP2, PAXIP1, WT1, MAPK8IP1, MAPK8, ID2,
Protein Size: 417

Molekulargewicht: 45 kDa

Gen-ID: 5076

NCBI Accession: NM_000278, NP_000269

UniProt: Q02962

Pathways: Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation