GCM1 Antikörper (C-Term)

Produktnummer ABIN2792609

Produktdetails anti-GCM1 Antikörper

Target: GCM1 (Glial Cells Missing Homolog 1 (GCM1))

Bindungsspezifität: C-Term

Reaktivität: Human, Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DFNSYVQSPA YHSPQEDPFL FTYASHPHQQ YSLPSKSSKW DFEEEMTYLG

Kreuzreaktivität: Hund, Human

Homologie: Dog: 90%, Horse: 92%, Human: 100%, Rabbit: 81%

Produktmerkmale: This is a rabbit polyclonal antibody against GCM1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GCM1

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-GCM1 Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 436 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GCM1 Antikörper (ABIN2792609)

Drewlo, Czikk, Baczyk, Lye, Kingdom: "Glial cell missing-1 mediates over-expression of tissue inhibitor of metalloproteinase-4 in severe pre-eclamptic placental villi." in: Human reproduction (Oxford, England), Vol. 26, Issue 5, pp. 1025-34, (2011) (PubMed).

Details zu GCM1

Target: GCM1 (Glial Cells Missing Homolog 1 (GCM1))

Andere Bezeichnung: GCM1 / GCMA (GCM1 Produkte)

Hintergrund: GCM1 is a DNA-binding protein with a gcm-motif (glial cell missing motif). GCM1 is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins.
Alias Symbols: GCMA, hGCMa
Protein Interaction Partner: FBXW2, UBC, SENP1, CAMK1, SUMO1, DUSP23, CREBBP, HDAC5, HDAC4, HDAC3, HDAC1, CUL1, SKP1, UBE2I,
Protein Size: 436

Molekulargewicht: 49 kDa

Gen-ID: 8521

NCBI Accession: NM_003643, NP_003634

UniProt: Q9NP62