GCM1 Antikörper (Glial Cells Missing Homolog 1 (Drosophila)) (C-Term)

Details for Product anti-GCM1 Antibody No. ABIN2792609, Anbieter: Anmelden zum Anzeigen
Antigen
  • GCM1
  • GCM
  • GCM-1
  • GCMA
  • hGCMa
  • GCMa
  • Gcm-rs2
  • Gcm1-rs1
  • glide
  • Gcma
  • glial cells missing homolog 1
  • glial cells missing homolog 1 (Drosophila)
  • GCM1
  • Gcm1
Epitop
C-Term
13
6
4
3
2
1
1
1
1
1
Reaktivität
Hund, Pferd, Human, Kaninchen
48
21
20
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
35
15
Klonalität
Polyklonal
Konjugat
Dieser GCM1 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
35
20
17
13
9
7
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human GCM1
Sequenz DFNSYVQSPA YHSPQEDPFL FTYASHPHQQ YSLPSKSSKW DFEEEMTYLG
Kreuzreaktivität Hund, Human
Homologie Dog: 90%, Horse: 92%, Human: 100%, Rabbit: 81%
Produktmerkmale This is a rabbit polyclonal antibody against GCM1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere GCM1 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung GCM1 / GCMA (GCM1 Antibody Abstract)
Hintergrund GCM1 is a DNA-binding protein with a gcm-motif (glial cell missing motif). GCM1 is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins.
Alias Symbols: GCMA, hGCMa
Protein Interaction Partner: FBXW2, UBC, SENP1, CAMK1, SUMO1, DUSP23, CREBBP, HDAC5, HDAC4, HDAC3, HDAC1, CUL1, SKP1, UBE2I,
Protein Size: 436
Molekulargewicht 49 kDa
Gen-ID 8521
NCBI Accession NM_003643, NP_003634
UniProt Q9NP62
Applikations-hinweise WB Suggested Anti-GCM1 Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 436 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Glial Cells Missing Homolog 1 (Drosophila) (GCM1) (C-Term) antibody (ABIN2792609) WB Suggested Anti-GCM1 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cel...
Western Blotting (WB) image for anti-Glial Cells Missing Homolog 1 (Drosophila) (GCM1) (C-Term) antibody (ABIN2792609) WB Suggested Anti-GCM1
Antibody Titration: 0.2-1 µg/mL
Positive Control...
Produkt verwendet in: Drewlo, Czikk, Baczyk, Lye, Kingdom: "Glial cell missing-1 mediates over-expression of tissue inhibitor of metalloproteinase-4 in severe pre-eclamptic placental villi." in: Human reproduction (Oxford, England), Vol. 26, Issue 5, pp. 1025-34, 2011 (PubMed).

Allgemeine Veröffentlichungen Chuang, Chang, Chang, Yao, Chen: "Histone deacetylase 3 binds to and regulates the GCMa transcription factor." in: Nucleic acids research, Vol. 34, Issue 5, pp. 1459-69, 2006 (PubMed).

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