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NR2C1 Antikörper (C-Term)

NR2C1 Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2792596
  • Target Alle NR2C1 Antikörper anzeigen
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    Bindungsspezifität
    • 13
    • 11
    • 10
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 65
    • 16
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Schwein
    Wirt
    • 58
    • 8
    Kaninchen
    Klonalität
    • 62
    • 4
    Polyklonal
    Konjugat
    • 39
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NR2C1 Antikörper ist unkonjugiert
    Applikation
    • 57
    • 30
    • 9
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    QEKAYVEFQD YITKTYPDDT YRLSRLLLRL PALRLMNATI TEELFFKGLI
    Kreuzreaktivität
    Rind (Kuh), Hund, Huhn, Human, Maus, Ratte (Rattus)
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against NR2C1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human NR2C1
    Top Product
    Discover our top product NR2C1 Primärantikörper
  • Applikationshinweise
    WB Suggested Anti-NR2C1 Antibody Titration: 2.5 µg/mL
    ELISA Titer: 1:312500
    Positive Control: HCT15 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 603 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    Andere Bezeichnung
    NR2C1 (NR2C1 Produkte)
    Synonyme
    TR2 antikoerper, NR2C1 antikoerper, dor2 antikoerper, tr2-11 antikoerper, xDOR2 antikoerper, DKFZp468M0512 antikoerper, si:dkey-183c16.2 antikoerper, zgc:110672 antikoerper, 4831444H07Rik antikoerper, 80.3 antikoerper, Eenr antikoerper, Tr2-11 antikoerper, Tr2 antikoerper, Psg4 antikoerper, TR2-11 antikoerper, PSG9 antikoerper, nr2c1 antikoerper, nuclear receptor subfamily 2 group C member 1 antikoerper, nuclear receptor subfamily 2 group C member 1 S homeolog antikoerper, nuclear receptor subfamily 2, group C, member 1 antikoerper, pregnancy specific beta-1-glycoprotein 4 antikoerper, nuclear receptor subfamily 2 group C member 1 L homeolog antikoerper, NR2C1 antikoerper, nr2c1.S antikoerper, nr2c1 antikoerper, Nr2c1 antikoerper, PSG4 antikoerper, nr2c1.L antikoerper
    Hintergrund
    The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites
    Alias Symbols: TR2
    Protein Interaction Partner: PSPC1, MBD3, SIN3A, RCOR1, KDM1A, POLD3, TRIM28, RBM39, MTA2, MTA1, HDAC3, NR2C2, SMARCA4, SFPQ, RBBP7, RBBP4, NONO, HDAC2, HDAC1, HCFC1, DNMT1, CHD4, NUDT3, UBC, PML, HDAC4, NRIP1, AR, ESR1,
    Protein Size: 603
    Molekulargewicht
    67 kDa
    Gen-ID
    7181
    NCBI Accession
    NM_003297, NP_003288
    UniProt
    Q15625
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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