Osteoprotegerin Antikörper (N-Term)
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- Target Alle Osteoprotegerin (TNFRSF11B) Antikörper anzeigen
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Hund, Schwein, Kaninchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Osteoprotegerin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LDISIKWTTQ ETFPPKYLHY DEETSHQLLC DKCPPGTYLK QHCTAKWKTV
- Homologie
- Dog: 78%, Horse: 78%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 78%, Rat: 78%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TNFRSF11B. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF11B
- Top Product
- Discover our top product TNFRSF11B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 401 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
- Andere Bezeichnung
- TNFRSF11B (TNFRSF11B Produkte)
- Synonyme
- CD254 antikoerper, ODF antikoerper, OPGL antikoerper, OPTB2 antikoerper, RANKL antikoerper, TRANCE antikoerper, hRANKL2 antikoerper, sOdf antikoerper, OCIF antikoerper, OPG antikoerper, TR1 antikoerper, Opg antikoerper, ocif antikoerper, opg antikoerper, tr1 antikoerper, TNF superfamily member 11 antikoerper, TNF receptor superfamily member 11b antikoerper, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antikoerper, TNF receptor superfamily member 11B antikoerper, tumor necrosis factor receptor superfamily member 11b S homeolog antikoerper, tumor necrosis factor receptor superfamily, member 11b antikoerper, TNFSF11 antikoerper, TNFRSF11B antikoerper, Tnfrsf11b antikoerper, tnfrsf11b.S antikoerper
- Substanzklasse
- Chemical
- Hintergrund
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TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Alias Symbols: OPG, TR1, OCIF
Protein Interaction Partner: TNFSF13, TNFSF10, TNFSF11, VWF, VTN, THBS1, FN1,
Protein Size: 401 - Molekulargewicht
- 46 kDa
- Gen-ID
- 4982
- NCBI Accession
- NM_002546, NP_002537
- UniProt
- O00300
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