DENND1C Antikörper (C-Term)

Produktnummer ABIN2790995

Produktdetails anti-DENND1C Antikörper

Target: DENND1C (DENN/MADD Domain Containing 1C (DENND1C))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DENND1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PSSLEDPRAR PPKALLAERA HLQPREEPGA LNSPATPTSN CQKSQPSSRP

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DENND1C. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND1C

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 801 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DENND1C

Target: DENND1C (DENN/MADD Domain Containing 1C (DENND1C))

Andere Bezeichnung: DENND1C (DENND1C Produkte)

Synonyme: FAM31C antikoerper, 4432409M07Rik antikoerper, DENN/MADD domain containing 1C L homeolog antikoerper, DENN/MADD domain containing 1C antikoerper, DENN domain containing 1C antikoerper, dennd1c.L antikoerper, DENND1C antikoerper, Dennd1c antikoerper

Hintergrund: Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
Alias Symbols: FAM31C
Protein Interaction Partner: APP, ELAVL1,
Protein Size: 801

Molekulargewicht: 87 kDa

Gen-ID: 79958

NCBI Accession: NM_024898, NP_079174

UniProt: Q8IV53