EIF2B3 Antikörper (Middle Region)

Produktnummer ABIN2790398

Produktdetails anti-EIF2B3 Antikörper

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ENGSITSIRS ELIPYLVRKQ FSSASSQQGQ EEKEEDLKKK ELKSLDIYSF

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Yeast: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF2B3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human EIF2B3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 452 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF2B3

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Andere Bezeichnung: EIF2B3 (EIF2B3 Produkte)

Synonyme: zgc:56473 antikoerper, 1190002P15Rik antikoerper, EIF-2B antikoerper, EIF2Bgamma antikoerper, eukaryotic translation initiation factor 2B subunit gamma L homeolog antikoerper, eukaryotic translation initiation factor 2B, subunit 3 gamma antikoerper, eukaryotic translation initiation factor 2B subunit gamma antikoerper, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa antikoerper, eukaryotic translation initiation factor 2B, subunit 3 antikoerper, eif2b3.L antikoerper, eif2b3 antikoerper, EIF2B3 antikoerper, Eif2b3 antikoerper

Hintergrund: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EIF-2B, EIF2Bgamma
Protein Interaction Partner: UBC, C14orf166, RTCB, DIMT1, NELFB, EDC4, IGF2BP3, G3BP1, EIF2B2, EIF3C, YBX3, RFC4, QARS, NMT1, HNRNPM, MRE11A, ILF2, HNRNPU, FLII, FKBP3, DHX9, DDX1, ABCF1, FBXO6, EGFR, EIF2B5, EIF2B4, NDUFB8, EIF2B3, GOLM1, EIF2S2, EIF2S1, STC2, EIF2B1,
Protein Size: 452

Molekulargewicht: 50 kDa

Gen-ID: 8891

NCBI Accession: NM_020365, NP_065098

UniProt: Q9NR50