SNTA1 Antikörper (N-Term)

Produktnummer ABIN2790311

Produktdetails anti-SNTA1 Antikörper

Target: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SPGPTPRNFS EAKHMSLKMA YVSKRCTPND PEPRYLEICS ADGQDTLFLR

Homologie: Cow: 79%, Guinea Pig: 86%, Horse: 82%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SNTA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human SNTA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SNTA1

Target: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Andere Bezeichnung: SNTA1 (SNTA1 Produkte)

Synonyme: SNTA1 antikoerper, MGC147484 antikoerper, AW228934 antikoerper, Snt1 antikoerper, LQT12 antikoerper, SNT1 antikoerper, TACIP1 antikoerper, dJ1187J4.5 antikoerper, syntrophin alpha 1 antikoerper, syntrophin, alpha 1 L homeolog antikoerper, syntrophin, alpha 1 antikoerper, syntrophin, acidic 1 antikoerper, SNTA1 antikoerper, snta1.L antikoerper, snta1 antikoerper, Snta1 antikoerper

Hintergrund: Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue.
Alias Symbols: SNT1, LQT12, TACIP1, dJ1187J4.5
Protein Size: 396

Molekulargewicht: 43 kDa

Gen-ID: 6640

NCBI Accession: NM_003098, NP_003089

UniProt: Q13424

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development