CTDP1 Antikörper (C-Term)

Produktnummer ABIN2790245

Produktdetails anti-CTDP1 Antikörper

Target: CTDP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 (CTDP1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Hund, Pferd, Schwein, Kaninchen, Ratte, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTDP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AHAPDKEPEL GGQEEGERDG LCGLGNGCAD RKEAETESQN SELSGVTAGE

Homologie: Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CTDP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTDP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 867 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CTDP1

Target: CTDP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 (CTDP1))

Andere Bezeichnung: CTDP1 (CTDP1 Produkte)

Synonyme: CTDP1 antikoerper, CCFDN antikoerper, FCP1 antikoerper, 4930563P03Rik antikoerper, AW553592 antikoerper, CTD phosphatase subunit 1 antikoerper, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 antikoerper, RNA polymerase II subunit A C-terminal domain phosphatase antikoerper, CTD phosphatase Fcp1 antikoerper, Ctdp1 antikoerper, CTDP1 antikoerper, ctdp1 antikoerper, ANI_1_2668024 antikoerper, AOR_1_1228154 antikoerper, CpipJ_CPIJ004583 antikoerper, PTRG_11566 antikoerper, SJAG_01286 antikoerper, MCYG_05528 antikoerper, VDBG_09811 antikoerper

Hintergrund: This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CCFDN, FCP1
Protein Interaction Partner: UBC, CDK9, UPP1, PPP2CA, PPP1CA, POLR2A, POLR2C, GRK5, ELP2, ELP3, SUMO2, PRKDC, CDK8, CDK7, INTS8, MED15, MED4, INTS6, INTS1, INTS7, MED16, MED6, MED24, MED7, MED26, MED17, MED23, MED14, MED1, MED8, MED25, INTS3, POLR2J, ERH, POLR2B, STK38, PRMT5, HIST1H
Protein Size: 867

Molekulargewicht: 93 kDa

Gen-ID: 9150

NCBI Accession: NM_048368, NP_430255

UniProt: Q9Y5B0