ARPC1B Antikörper (C-Term)

Produktnummer ABIN2790242

Produktdetails anti-ARPC1B Antikörper

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARPC1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RERFQNLDKK ASSEGGTAAG AGLDSLHKNS VSQISVLSGG KAKCSQFCTT

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 100%, Human: 100%, Mouse: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARPC1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ARPC1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 372 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARPC1B

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Andere Bezeichnung: ARPC1B (ARPC1B Produkte)

Synonyme: ARC41 antikoerper, p40-ARC antikoerper, p41-ARC antikoerper, cb871 antikoerper, arpc1a antikoerper, fj15h02 antikoerper, zgc:64056 antikoerper, wu:fj08e12 antikoerper, wu:fj15h02 antikoerper, 41kDa antikoerper, AA408064 antikoerper, AA408534 antikoerper, AA571392 antikoerper, AF007010 antikoerper, AW208418 antikoerper, L72 antikoerper, SOP2Hs antikoerper, ACTIN-RELATED PROTEIN C1 antikoerper, ARPC1 antikoerper, F16D14.14 antikoerper, F16D14_14 antikoerper, actin-related protein C1B antikoerper, arc41 antikoerper, p40-arc antikoerper, p41-arc antikoerper, actin related protein 2/3 complex subunit 1B antikoerper, actin related protein 2/3 complex, subunit 1B antikoerper, ARP2/3 complex 41 kDa subunit antikoerper, actin-related protein C1B antikoerper, actin-related protein 2/3 complex subunit 1B antikoerper, actin related protein 2/3 complex subunit 1B S homeolog antikoerper, ARPC1B antikoerper, Arpc1b antikoerper, EHI_094120 antikoerper, arpc1b antikoerper, LOC100410640 antikoerper, arpc1b.S antikoerper

Hintergrund: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
Alias Symbols: ARC41, p40-ARC, p41-ARC
Protein Interaction Partner: SUMO2, UBC, SUMO1, NEDD8, BTF3L4, C14orf142, IPO11, TPRKB, PDCD4, ANP32B, ARPC2, ACTR2, ACTR3, ARPC3, ARPC4, ARPC5, TOM1L1, ANP32A, VBP1, UBE3A, TPD52L2, TPD52, RPA2, RANGAP1, PRKACB, PPP2R5D, METTL1, HSF1, DR1, DHPS, CALU, CALR, AARS, SRPK2, PAN2, WASL,
Protein Size: 372

Molekulargewicht: 41 kDa

Gen-ID: 10095

NCBI Accession: NM_005720, NP_005711

UniProt: O15143

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization