CPI-17 Antikörper (N-Term)

Produktnummer ABIN2789677

Produktdetails anti-CPI-17 Antikörper

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPI-17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GKRVLSKLQS PSRARGPGGS PGGLQKRHAR VTVKYDRREL QRRLDVEKWI

Homologie: Cow: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PPP1R14A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 147 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CPI-17 Antikörper (ABIN2789677)

Xiong, Xia, Tang, Pan, Mei, Xiong: "Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response." in: EBioMedicine, Vol. 9, pp. 45-60, (2016) (PubMed).

Details zu CPI-17

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Andere Bezeichnung: PPP1R14A (PPP1R14A Produkte)

Synonyme: MGC81874 antikoerper, cpi-17 antikoerper, ppp1inl antikoerper, CPI-17 antikoerper, im:7147597 antikoerper, ppp1r14a antikoerper, zgc:110700 antikoerper, PPP1R14A antikoerper, CPI17 antikoerper, PPP1INL antikoerper, Cpi17 antikoerper, 1110001M11Rik antikoerper, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog antikoerper, protein phosphatase 1 regulatory inhibitor subunit 14A antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 14A antikoerper, ppp1r14a.L antikoerper, ppp1r14a antikoerper, ppp1r14aa antikoerper, PPP1R14A antikoerper, Ppp1r14a antikoerper

Hintergrund: The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: CPI-17, CPI17, PPP1INL
Protein Interaction Partner: cki1, CSNK1G1, YWHAZ, PRKCZ, PRKD1, PRKCH, PRKCE, PRKCA, CSNK1G3, CSNK1G2, CSNK1E, CSNK1D, CSNK1A1, APP, PRNP, UBC, PRKCG,
Protein Size: 147

Molekulargewicht: 17 kDa

Gen-ID: 94274

NCBI Accession: NM_033256, NP_150281

UniProt: Q96A00