ARTN Antikörper (Middle Region)

Produktnummer ABIN2789666

Produktdetails anti-ARTN Antikörper

Target: ARTN (Artemin (ARTN))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARTN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RTARWCSGRA RRPPPQPSRP APPPPAPPSA LPRGGRAARA GGPGSRARAA

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ARTN. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 228 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARTN

Target: ARTN (Artemin (ARTN))

Andere Bezeichnung: ARTN (ARTN Produkte)

Synonyme: ARTN antikoerper, ENOVIN antikoerper, EVN antikoerper, NBN antikoerper, neublastin antikoerper, artemin antikoerper, ARTN antikoerper, Artn antikoerper

Hintergrund: The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ENOVIN, EVN, NBN
Protein Interaction Partner: GFRA3, ARTN,
Protein Size: 228

Molekulargewicht: 19 kDa

Gen-ID: 9048

NCBI Accession: NM_057090, NP_476431