TNFSF8 Antikörper (N-Term)

Produktnummer ABIN2789625

Produktdetails anti-TNFSF8 Antikörper

Target: TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFSF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ATIMVLVVQR TDSIPNSPDN VPLKGGNCSE DLLCILKRAP FKKSWAYLQV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TNFSF8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 234 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNFSF8

Target: TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))

Andere Bezeichnung: TNFSF8 (TNFSF8 Produkte)

Synonyme: CD153 antikoerper, CD30LG antikoerper, Cd30l antikoerper, CD30L antikoerper, TNFRSF8 antikoerper, TNFSF8 antikoerper, tumor necrosis factor (ligand) superfamily, member 8 antikoerper, TNF superfamily member 8 antikoerper, tumor necrosis factor superfamily member 8 antikoerper, Tnfsf8 antikoerper, TNFSF8 antikoerper

Hintergrund: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD153, CD30L, CD30LG, MGC138144
Protein Interaction Partner: TNFRSF8, ANG,
Protein Size: 234

Molekulargewicht: 26 kDa

Gen-ID: 944

NCBI Accession: NM_001244, NP_001235

UniProt: P32971