Ephrin B3 Antikörper (C-Term)

Produktnummer ABIN2789618

Produktdetails anti-Ephrin B3 Antikörper

Target: Ephrin B3 (EFNB3)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AGAGGAMCWR RRRAKPSESR HPGPGSFGRG GSLGLGGGGG MGPREAEPGE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Efnb3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Efnb3

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Ephrin B3

Target: Ephrin B3 (EFNB3)

Andere Bezeichnung: Efnb3 (EFNB3 Produkte)

Synonyme: efnb3-A antikoerper, EphB3 antikoerper, EFNB3 antikoerper, efnb3 antikoerper, id:ibd5049 antikoerper, zgc:111938 antikoerper, EFL-6 antikoerper, ELF-3 antikoerper, Elk-L3 antikoerper, Epl8 antikoerper, LERK-8 antikoerper, NLERK-2 antikoerper, ELK-L3 antikoerper, RGD1565678 antikoerper, EFL6 antikoerper, EPLG8 antikoerper, LERK8 antikoerper, ephrin B3 antikoerper, ephrin-B3 L homeolog antikoerper, ephrin-B3b antikoerper, ephrin-B3 antikoerper, EFNB3 antikoerper, efnb3.L antikoerper, efnb3b antikoerper, efnb3 antikoerper, Efnb3 antikoerper

Hintergrund: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb3 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. It may play a pivotal role in forebrain function. It binds to, and induce the collapse of, commissural axons/growth cones in vitro. Efnb3 may play a role in constraining the orientation of longitudinally projecting axons.
Alias Symbols: EFL-6, ELF-3, Elk-L3, Epl8, LERK-8, NLERK-2
Protein Size: 340

Molekulargewicht: 36 kDa

Gen-ID: 13643

NCBI Accession: NM_007911, NP_031937

UniProt: O35393

Pathways: RTK Signalweg