FPGS Antikörper (Middle Region)

Produktnummer ABIN2789500

Produktdetails anti-FPGS Antikörper

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FPGS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: CWLQRQDRHG AGEPKASRPG LLWQLPLAPV FQPTSHMRLG LRNTEWPGRT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FPGS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 537 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FPGS Antikörper (ABIN2789500)

Fukuda, Oguri, Kunii, Sone, Uemura, Takakuwa, Maeno, Kanemitsu, Ohkubo, Takemura, Ito, Niimi: "A folylpoly-γ-glutamate synthase single nucleotide polymorphism associated with response to pemetrexed treatment combined with platinum for non-small cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 102, pp. 15-20, (2016) (PubMed).

Details zu FPGS

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Andere Bezeichnung: FPGS (FPGS Produkte)

Synonyme: zgc:63807 antikoerper, wu:fk49h03 antikoerper, wu:fk51d09 antikoerper, FPGS antikoerper, fpgS antikoerper, SCC88.25c antikoerper, BA4689 antikoerper, AA408187 antikoerper, folylpolyglutamate synthase antikoerper, dihydrofolate synthase antikoerper, folylpolyglutamate synthase, mitochondrial antikoerper, folylpolyglutamyl synthetase antikoerper, fpgs antikoerper, fpgS antikoerper, FPGS antikoerper, SCO2614 antikoerper, fgs antikoerper, folC antikoerper, CpipJ_CPIJ008043 antikoerper, Fpgs antikoerper

Hintergrund: This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms.
Alias Symbols: -
Protein Interaction Partner: UBC,
Protein Size: 537

Molekulargewicht: 59 kDa

Gen-ID: 2356

NCBI Accession: NM_001018078, NP_001018088

UniProt: Q5JU19