EPM2A Antikörper (N-Term)

Produktnummer ABIN2789472

Produktdetails anti-EPM2A Antikörper

Target: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPM2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ALALQEPGLW LGEVELAAEE AAQDGAEPGR VDTFWYKFLK REPGGELSWE

Homologie: Cow: 100%, Dog: 90%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EPM2A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 317 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EPM2A

Target: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Andere Bezeichnung: EPM2A (EPM2A Produkte)

Synonyme: TG-B antikoerper, Tg(TcraK,TcrbK)TG-BFlv antikoerper, EPM2 antikoerper, MELF antikoerper, laforin antikoerper, EPM2A, laforin glucan phosphatase antikoerper, epilepsy, progressive myoclonic epilepsy, type 2 gene alpha antikoerper, EPM2A antikoerper, Epm2a antikoerper

Hintergrund: This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants.
Alias Symbols: EPM2, MELF
Protein Interaction Partner: NHLRC1, EPM2A, PPP1R3D, PRKAA1, STUB1, PRKAB2, PRKAA2, PPP1R3C, UBC, GSK3B, NFU1, EPM2AIP1, UBE2D1, HSPA5,
Protein Size: 317

Molekulargewicht: 35 kDa

Gen-ID: 7957

NCBI Accession: NM_001018041, NP_001018051

Pathways: Cellular Glucan Metabolic Process