PD-L1 Antikörper (C-Term)
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- Target Alle PD-L1 Antikörper anzeigen
- PD-L1 (CD274 (PD-L1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PD-L1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- HLVILGAILL CLGVALTFIF RLRKGRMMDV KKCGIQDTNS KKQSDTHLEE
- Homologie
- Horse: 82%, Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CD274. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of CD274
- Top Product
- Discover our top product PD-L1 Primärantikörper
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anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reaktivität: Human WB, FACS, ELISA, IF Wirt: Ziege Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reaktivität: Human WB, FACS, IHC, ELISA, IF Wirt: Maus Monoclonal 9B5F4 unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reaktivität: Human WB, FACS, IHC, ELISA, ICC, Neut Wirt: Maus Monoclonal 6D9A2 unconjugated
anti-CD274 (PD-L1) (AA 39-191) antibodyPD-L1 Reaktivität: Human, Maus WB, FACS, IHC, ELISA, IF, Coat, StM Wirt: Maus Monoclonal PDL1-2746 unconjugated
anti-CD274 (PD-L1) (AA 48-290) antibodyPD-L1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 34-241) antibodyPD-L1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reaktivität: Human WB, FACS, IHC, ELISA, ICC Wirt: Maus Monoclonal 7D2A10 unconjugated
anti-CD274 (PD-L1) (C-Term) antibodyKO Validated PD-L1 Reaktivität: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) antibodyKO Validated PD-L1 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 290 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PD-L1 (CD274 (PD-L1))
- Andere Bezeichnung
- CD274 (PD-L1 Produkte)
- Synonyme
- B7-H antikoerper, B7H1 antikoerper, PD-L1 antikoerper, PDCD1L1 antikoerper, PDCD1LG1 antikoerper, PDL1 antikoerper, A530045L16Rik antikoerper, B7h1 antikoerper, Pdcd1l1 antikoerper, Pdcd1lg1 antikoerper, Pdl1 antikoerper, RGD1566211 antikoerper, CD274 molecule antikoerper, CD274 antigen antikoerper, programmed cell death 1 ligand 2 antikoerper, CD274 antikoerper, Cd274 antikoerper, PDCD1LG2 antikoerper
- Hintergrund
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CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Alias Symbols: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Protein Interaction Partner: PDCD1, CD80, PTPN11,
Protein Size: 290 - Molekulargewicht
- 32 kDa
- Gen-ID
- 29126
- NCBI Accession
- NM_014143, NP_054862
- UniProt
- Q9NZQ7
- Pathways
- Cancer Immune Checkpoints
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