IKKi/IKKe Antikörper (N-Term)

Produktnummer ABIN2789403

Produktdetails anti-IKKi/IKKe Antikörper

Target: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IKKi/IKKe Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AGAIAGAQRR ENGPLEWSYT LPITCQLSLG LQSQLVPILA NILEVEQAKC

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IKBKE. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 631 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IKKi/IKKe

Target: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Andere Bezeichnung: IKBKE (IKBKE Produkte)

Synonyme: zgc:100844 antikoerper, IKBKE antikoerper, MGC130907 antikoerper, IKK-E antikoerper, IKK-i antikoerper, IKKE antikoerper, IKKI antikoerper, AW558201 antikoerper, IKKepsilon antikoerper, Ikki antikoerper, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon antikoerper, inhibitor of nuclear factor kappa B kinase subunit epsilon antikoerper, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog antikoerper, inhibitor of kappaB kinase epsilon antikoerper, IKBKE antikoerper, ikbke antikoerper, ikbke.L antikoerper, Ikbke antikoerper

Hintergrund: IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines.
Alias Symbols: IKK-i, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297, IKK-E
Protein Interaction Partner: CD209, TRIM6, UBC, TRAF3, NMRAL1, DDX58, MAFB, MYD88, IKBKB, HSP90AA1, DDX3X, CYLD, BIRC3, BIRC2, AZI2, TRAF3IP2, TANK, TBKBP1, IKBKE, IKBKG, TRAF2, RNF11, NFKBIA, TOPORS, SUMO1, SUMO2, SUMO3, TRIM27, PML, MAVS, TBK1, MBP, TNIP1, TAX1BP1, TNFAIP3, IRF3, C
Protein Size: 631

Molekulargewicht: 69 kDa

Gen-ID: 9641

NCBI Accession: NM_001193321, NP_001180250

UniProt: Q3B754

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades