POLG2 Antikörper (N-Term)

Produktnummer ABIN2788963

Produktdetails anti-POLG2 Antikörper

Target: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KSHAELEGNG EHPEAPGSGE GSEALLEICQ RRHFLSGSKQ QLSRDSLLSG

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against POLG2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 485 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu POLG2

Target: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Andere Bezeichnung: POLG2 (POLG2 Produkte)

Synonyme: POLG2 antikoerper, im:7158733 antikoerper, si:ch211-157f15.3 antikoerper, HP55 antikoerper, MTPOLB antikoerper, PEOA4 antikoerper, POLB antikoerper, POLG-BETA antikoerper, POLGB antikoerper, mtpolb antikoerper, DNA polymerase gamma 2, accessory subunit antikoerper, polymerase (DNA directed), gamma 2, accessory subunit antikoerper, polymerase (DNA directed), gamma 2, accessory subunit L homeolog antikoerper, Polg2 antikoerper, POLG2 antikoerper, polg2 antikoerper, polg2.L antikoerper

Hintergrund: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
Alias Symbols: HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB
Protein Interaction Partner: PARP1, SUMO1,
Protein Size: 485

Molekulargewicht: 53 kDa

Gen-ID: 11232

NCBI Accession: NM_007215, NP_009146

UniProt: Q9UHN1