PFKFB1 Antikörper (C-Term)

Produktnummer ABIN2788933

Produktdetails anti-PFKFB1 Antikörper

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKFB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CPLHTVLKLT PVAYGCKVES IYLNVEAVNT HREKPENVDI TREPEEALDT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PFKFB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 471 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PFKFB1

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Andere Bezeichnung: PFKFB1 (PFKFB1 Produkte)

Synonyme: zgc:55328 antikoerper, wu:fi11h10 antikoerper, PFKFB1 antikoerper, F6PK antikoerper, HL2K antikoerper, PFRX antikoerper, Pfkfb01 antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 antikoerper, pfkfb1 antikoerper, PFKFB1 antikoerper, pfkfb1.S antikoerper, LOC100475853 antikoerper, Pfkfb1 antikoerper

Hintergrund: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Alias Symbols: F6PK, HL2K, MGC116715, MGC116717, PFRX
Protein Interaction Partner: PFKFB1, Prkaa2, PRKCA, PRKACA, APP, AKT1, MAPK3,
Protein Size: 471

Molekulargewicht: 52 kDa

Gen-ID: 5207

NCBI Accession: NM_002625, NP_002616

UniProt: Q4VBA8

Pathways: Regulation of Carbohydrate Metabolic Process