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PRKAR2A Antikörper (Middle Region)

PRKAR2A Reaktivität: Human, Ratte, Maus, Hund, Schwein, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788839
  • Target Alle PRKAR2A Antikörper anzeigen
    PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))
    Bindungsspezifität
    • 16
    • 10
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Ratte, Maus, Hund, Schwein, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen
    Wirt
    • 45
    • 5
    • 1
    Kaninchen
    Klonalität
    • 37
    • 14
    Polyklonal
    Konjugat
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PRKAR2A Antikörper ist unkonjugiert
    Applikation
    • 39
    • 14
    • 14
    • 13
    • 12
    • 8
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    DILVTKDNQT RSVGQYDNRG SFGELALMYN TPRAATIVAT SEGSLWGLDR
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PRKAR2A. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product PRKAR2A Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 404 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))
    Andere Bezeichnung
    PRKAR2A (PRKAR2A Produkte)
    Synonyme
    PKR2 antikoerper, PRKAR2 antikoerper, prkar2a antikoerper, zgc:85886 antikoerper, PRKAR2A antikoerper, 1110061A24Rik antikoerper, AI317181 antikoerper, AI836829 antikoerper, RII(alpha) antikoerper, protein kinase cAMP-dependent type II regulatory subunit alpha antikoerper, protein kinase, cAMP-dependent, regulatory, type II, alpha, B antikoerper, protein kinase, cAMP-dependent, regulatory, type II, alpha antikoerper, protein kinase, cAMP dependent regulatory, type II alpha antikoerper, protein kinase cAMP-dependent type 2 regulatory subunit alpha antikoerper, PRKAR2A antikoerper, prkar2ab antikoerper, Prkar2a antikoerper
    Hintergrund
    CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).
    Alias Symbols: MGC3606, PKR2, PRKAR2
    Protein Interaction Partner: UBC, SUZ12, IMPDH2, GPS1, CSRP1, KPNA6, PRKACB, PRKACA, GCH1, WASF1, VCP, CIRBP, ELAVL1, PJA2, Dynll1, AKAP7, PPP1CB, MYCBPAP, ARFGEF2, AKAP2, RAB32, NBEA, AKAP12, AKAP11, AKAP10, AKAP8, AKAP6, AKAP3, AKAP5, AKAP13, AKAP9, CBFA2T3, SMAD3, AKAP1, CFTR, SMA
    Protein Size: 404
    Molekulargewicht
    44 kDa
    Gen-ID
    5576
    NCBI Accession
    NM_004157, NP_004148
    UniProt
    P13861
    Pathways
    Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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