PANK2 Antikörper (Middle Region)

Produktnummer ABIN2788602

Produktdetails anti-PANK2 Antikörper

Target: PANK2 (Pantothenate Kinase 2 (PANK2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PANK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FGLPGWAVAS SFGNMMSKEK REAVSKEDLA RATLITITNN IGSIARMCAL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PANK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of HUMAN PANK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PANK2

Target: PANK2 (Pantothenate Kinase 2 (PANK2))

Andere Bezeichnung: PANK2 (PANK2 Produkte)

Synonyme: ATPANK2 antikoerper, F10M6.180 antikoerper, F10M6_180 antikoerper, pantothenate kinase 2 antikoerper, PANK2 antikoerper, C20orf48 antikoerper, HARP antikoerper, HSS antikoerper, NBIA1 antikoerper, PKAN antikoerper, 4933409I19Rik antikoerper, AI642621 antikoerper, pantothenate kinase 2 antikoerper, pantothenate kinase 2, mitochondrial antikoerper, ribonuclease A family member 11 (inactive) antikoerper, PANK2 antikoerper, Tsp_01576 antikoerper, LOC100539295 antikoerper, Pank2 antikoerper, RNASE11 antikoerper

Hintergrund: This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.
Protein Interaction Partner: UBC, DHX36, QRICH2, LXN, YWHAQ, VDAC1, RASGRF2,
Protein Size: 460

Molekulargewicht: 50 kDa

Gen-ID: 80025

Pathways: Ribonucleoside Biosynthetic Process