CYP7B1 Antikörper (C-Term)

Produktnummer ABIN2788601

Produktdetails anti-CYP7B1 Antikörper

Target: CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))

Bindungsspezifität: C-Term

Reaktivität: Human, Rind (Kuh), Schwein, Kaninchen, Hund, Pferd, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP7B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AMYYLLRHPE AMAAVRDEID RLLQSTGQKK GSGFPIHLTR EQLDSLICLE

Homologie: Cow: 85%, Dog: 93%, Horse: 93%, Human: 100%, Pig: 86%, Rabbit: 85%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CYP7B1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP7B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 506 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CYP7B1

Target: CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))

Andere Bezeichnung: CYP7B1 (CYP7B1 Produkte)

Synonyme: CYP7B1 antikoerper, CBAS3 antikoerper, CP7B antikoerper, SPG5A antikoerper, AW261589 antikoerper, D3Ertd552e antikoerper, hct-1 antikoerper, cytochrome P450 family 7 subfamily B member 1 antikoerper, cytochrome P450, family 7, subfamily B, polypeptide 1 antikoerper, cytochrome P450, family 7, subfamily b, polypeptide 1 antikoerper, CYP7B1 antikoerper, cyp7b1 antikoerper, Cyp7b1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
Alias Symbols: CBAS3, CP7B, SPG5A
Protein Interaction Partner: UBC,
Protein Size: 506

Molekulargewicht: 58 kDa

Gen-ID: 9420

NCBI Accession: NM_004820, NP_004811

UniProt: O75881

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Intracellular Steroid Hormone Receptor Signaling