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PYM Antikörper (Middle Region)

WIBG Reaktivität: Human, Maus, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Ratte, Saccharomyces cerevisiae, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788484
  • Target Alle PYM (WIBG) Antikörper anzeigen
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 2
    • 1
    Middle Region
    Reaktivität
    • 30
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Ratte, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
    Wirt
    • 28
    • 2
    Kaninchen
    Klonalität
    • 28
    • 2
    Polyklonal
    Konjugat
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PYM Antikörper ist unkonjugiert
    Applikation
    • 22
    • 15
    • 13
    • 6
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    GLSKTAKRNL KRKEKRRQQQ EKEAEALSRT LDKVSLGDTA QIPSALQGPQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 82%, Zebrafish: 91%
    Produktmerkmale
    This is a rabbit polyclonal antibody against Wibg. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Mouse Wibg
    Top Product
    Discover our top product WIBG Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    Andere Bezeichnung
    Wibg (WIBG Produkte)
    Synonyme
    BEST:HL05757 antikoerper, CG10330 antikoerper, CG30176 antikoerper, Dmel\\CG30176 antikoerper, PYM antikoerper, Pym antikoerper, UD3 antikoerper, A030010B05Rik antikoerper, zgc:65891 antikoerper, zgc:77281 antikoerper, Partner of Y14 and Mago antikoerper, Wibg protein antikoerper, PYM homolog 1, exon junction complex associated factor L homeolog antikoerper, PYM homolog 1, exon junction complex associated factor antikoerper, Pym antikoerper, wibg antikoerper, pym1.L antikoerper, PYM1 antikoerper, Pym1 antikoerper, pym1 antikoerper
    Hintergrund
    Wibg is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. It acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Wibg interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions.
    Alias Symbols: A030010B05Rik, Pym
    Protein Size: 202
    Molekulargewicht
    22 kDa
    Gen-ID
    78428
    NCBI Accession
    NM_001170869, NP_001164340
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