CYP51A1 Antikörper (N-Term)

Produktnummer ABIN2788354

Produktdetails anti-CYP51A1 Antikörper

Target: CYP51A1 (Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP51A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TYLLGSDAAA LLFNSKNEDL NAEDVYSRLT TPVFGKGVAY DVPNPVFLEQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CYP51A1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CYP51A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 509 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CYP51A1

Target: CYP51A1 (Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1))

Andere Bezeichnung: CYP51A1 (CYP51A1 Produkte)

Synonyme: CP51 antikoerper, CYP51 antikoerper, CYPL1 antikoerper, LDM antikoerper, P450-14DM antikoerper, P450L1 antikoerper, cyp51a1 antikoerper, cytochrome P450 family 51 subfamily A member 1 antikoerper, cytochrome P450, family 51, subfamily A, polypeptide 1 antikoerper, cytochrome P450 family 51 subfamily A member 1 L homeolog antikoerper, CYP51A1 antikoerper, cyp51a1 antikoerper, cyp51a1.L antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
Protein Interaction Partner: UBC, ZNF420, ELAVL1,
Protein Size: 509

Molekulargewicht: 57 kDa

Gen-ID: 1595

NCBI Accession: NM_000786, NP_000777

UniProt: Q16850