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CYP24A1 Antikörper (C-Term)

CYP24A1 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788352
  • Target Alle CYP24A1 Antikörper anzeigen
    CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
    Bindungsspezifität
    • 15
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 42
    • 24
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen
    Wirt
    • 39
    • 3
    • 1
    Kaninchen
    Klonalität
    • 41
    • 2
    Polyklonal
    Konjugat
    • 29
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYP24A1 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 14
    • 13
    • 13
    • 11
    • 9
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    QVLGSSEDNF EDSSQFRPER WLQEKEKINP FAHLPFGVGK RMCIGRRLAE
    Homologie
    Dog: 79%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CYP24A1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CYP24A1
    Top Product
    Discover our top product CYP24A1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 514 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
    Andere Bezeichnung
    CYP24A1 (CYP24A1 Produkte)
    Synonyme
    CP24 antikoerper, CYP24 antikoerper, HCAI antikoerper, P450-CC24 antikoerper, 24-OHase antikoerper, Cyp24 antikoerper, 25-hydroxyvitaminD324-hydroxylase antikoerper, VITD12 antikoerper, CP450CC24 antikoerper, cytochrome P450 family 24 subfamily A member 1 antikoerper, cytochrome P450, family 24, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 24, subfamily A, polypeptide 1 antikoerper, CYP24A1 antikoerper, Cyp24a1 antikoerper
    Hintergrund
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: CP24, CYP24, MGC126273, MGC126274, P450-CC24, HCAI
    Protein Interaction Partner: Dlg4, UBC,
    Protein Size: 514
    Molekulargewicht
    55 kDa
    Gen-ID
    1591
    NCBI Accession
    NM_000782, NP_000773
    UniProt
    Q07973
    Pathways
    Metabolism of Steroid Hormones and Vitamin D
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