CYP11B1 Antikörper (Middle Region)

Produktnummer ABIN2788350

Produktdetails anti-CYP11B1 Antikörper

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP11B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LALFGERLGL VGHSPSSASL NFLHALEVMF KSTVQLMFMP RSLSRWTSPK

Homologie: Horse: 79%, Human: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CYP11B1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP11B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 503 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CYP11B1

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Andere Bezeichnung: CYP11B1 (CYP11B1 Produkte)

Synonyme: CPN1 antikoerper, CYP11B antikoerper, FHI antikoerper, P450C11 antikoerper, AA389061 antikoerper, Cyp11b antikoerper, Cyp11b-1 antikoerper, Cp11ba antikoerper, RATCP11BA antikoerper, P450c11 antikoerper, cytochrome P450, family 11, subfamily B, polypeptide 1 antikoerper, cytochrome P450 family 11 subfamily B member 1 antikoerper, cytochrome P450, family 11, subfamily b, polypeptide 1 antikoerper, cytochrome P450, subfamily XI B, polypeptide 1 antikoerper, CYP11B1 antikoerper, Cyp11b1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: CPN1, CYP11B, DKFZp686B05283, FHI, FLJ36771, P450C11
Protein Interaction Partner: CYP11B2,
Protein Size: 503

Molekulargewicht: 55 kDa

Gen-ID: 1584

NCBI Accession: NM_000497, NP_000488

UniProt: P15538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis