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CYP3A5 Antikörper (N-Term)

CYP3A5 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Schaf WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788347
  • Target Alle CYP3A5 Antikörper anzeigen
    CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Schaf
    Wirt
    • 20
    • 3
    Kaninchen
    Klonalität
    • 21
    • 2
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYP3A5 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    AITDPDVIRT VLVKECYSVF TNRRSLGPVG FMKSAISLAE DEEWKRIRSL
    Homologie
    Cow: 79%, Dog: 91%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 79%, Sheep: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CYP3A5. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CYP3A5
    Top Product
    Discover our top product CYP3A5 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 502 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
    Andere Bezeichnung
    CYP3A5 (CYP3A5 Produkte)
    Synonyme
    CP35 antikoerper, CYPIIIA5 antikoerper, P450PCN3 antikoerper, PCN3 antikoerper, cytochrome P450 family 3 subfamily A member 5 antikoerper, CYP3A5 antikoerper
    Hintergrund
    This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene.
    Alias Symbols: CP35, P450PCN3, PCN3, CYPIIIA5
    Protein Interaction Partner: RDH13, ATOH8, ETV5,
    Protein Size: 502
    Molekulargewicht
    57 kDa
    Gen-ID
    1577
    NCBI Accession
    NM_000777, NP_000768
    UniProt
    P51589
    Pathways
    Steroid Hormone Biosynthesis
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