COL1A1 Antikörper (C-Term)

Produktnummer ABIN2788299

Produktdetails anti-COL1A1 Antikörper

Target: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YRADDANVVR DRDLEVDTTL KSLSQQIENI RSPEGSRKNP ARTCRDLKMC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against COL1A1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human COL1A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1464 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COL1A1

Target: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Andere Bezeichnung: COL1A1 (COL1A1 Produkte)

Synonyme: OI4 antikoerper, Col1a-1 antikoerper, Cola-1 antikoerper, Cola1 antikoerper, Mov-13 antikoerper, Mov13 antikoerper, COLIA1 antikoerper, col1a1 antikoerper, MGC52532 antikoerper, COL1A1 antikoerper, COL1A2 antikoerper, alpha1(I) antikoerper, cb21 antikoerper, sb:cb21 antikoerper, sb:cb384 antikoerper, wu:fa99c12 antikoerper, wu:fb02c06 antikoerper, alpha3(I) antikoerper, col1a3 antikoerper, hm:zeh0348 antikoerper, wu:fa95h05 antikoerper, wu:fd02a10 antikoerper, wu:fj59a10 antikoerper, collagen type I alpha 1 chain antikoerper, collagen, type I, alpha 1 antikoerper, collagen, type I, alpha 1 S homeolog antikoerper, collagen alpha-1(I) chain antikoerper, collagen type I alpha 2 chain antikoerper, collagen, type I, alpha 1a antikoerper, collagen 1a1 antikoerper, collagen, type I, alpha 1b antikoerper, COL1A1 antikoerper, Col1a1 antikoerper, col1a1.S antikoerper, LOC397571 antikoerper, COL1A2 antikoerper, col1a1a antikoerper, col1a1 antikoerper, col1a1b antikoerper

Hintergrund: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Alias Symbols: OI4
Protein Interaction Partner: PDGFB, PDGFA, COL1A2, COL1A1, CAPN1, UBC, BRCA1, BARD1, C12orf57, RNH1, ATP13A2, ELAVL1, ACHE, TMPRSS6, P4HB, PAK1, HTRA1, MATN2, PRELP, TGFBI, BGN, VWF, ITGA2, DDR2, THBS1, TXN, SPARC, CD36, FGF7, IGFBP3, ITGA5, FN1, NID1, DCN, CD93, MMP9, MMP2, COL7A1,
Protein Size: 1464

Molekulargewicht: 137 kDa

Gen-ID: 1277

NCBI Accession: NM_000088, NP_000079

UniProt: P02452

Pathways: Sensory Perception of Sound, Autophagie, Growth Factor Binding