Melanophilin Antikörper (C-Term)

Produktnummer ABIN2788093

Produktdetails anti-Melanophilin Antikörper

Target: Melanophilin (MLPH)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Melanophilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NLPIFLPRVA GKLGKRPEDP NADPSSEAKA MAVPYLLRRK FSNSLKSQGK

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MLPH. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MLPH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 600 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Melanophilin

Target: Melanophilin (MLPH)

Andere Bezeichnung: MLPH (MLPH Produkte)

Synonyme: MGC155106 antikoerper, LOC100222096 antikoerper, 2210418F23Rik antikoerper, 5031433I09Rik antikoerper, AW228792 antikoerper, D1Wsu84e antikoerper, Slac-2a antikoerper, l(1)-3Rk antikoerper, l1Rk3 antikoerper, ln antikoerper, SLAC2-A antikoerper, melanophilin antikoerper, MLPH antikoerper, mlph antikoerper, Mlph antikoerper

Hintergrund: This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: MGC2771, MGC59733, SLAC2-A
Protein Interaction Partner: CUL2, UBC, RAB27B, RAB27A, MYO5A, RAB10, RPH3A, ACTA1,
Protein Size: 600

Molekulargewicht: 66 kDa

Gen-ID: 79083

NCBI Accession: NM_024101, NP_077006

UniProt: Q9BV36