PSMD9 Antikörper (Middle Region)

Produktnummer ABIN2788031

Produktdetails anti-PSMD9 Antikörper

Target: PSMD9 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 9 (PSMD9))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Kaninchen, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QVRTARHNII CLQNDHKAVM KQVEEALHQL HARDKEKQAR DMAEAHKEAM

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMD9. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PSMD9

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 223 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMD9

Target: PSMD9 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 9 (PSMD9))

Andere Bezeichnung: PSMD9 (PSMD9 Produkte)

Synonyme: Rpn4 antikoerper, p27 antikoerper, Bridge antikoerper, Bridge-1 antikoerper, zgc:92643 antikoerper, wu:fb30g07 antikoerper, PSMD9 antikoerper, psmd9 antikoerper, DDBDRAFT_0202482 antikoerper, DDBDRAFT_0232989 antikoerper, DDB_0202482 antikoerper, DDB_0232989 antikoerper, 1500011J20Rik antikoerper, 2610202L11Rik antikoerper, P27 antikoerper, proteasome 26S subunit, non-ATPase 9 antikoerper, proteasome 26S subunit, non-ATPase 9 L homeolog antikoerper, 26S proteasome non-ATPase regulatory subunit 9 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 antikoerper, PSMD9 antikoerper, Psmd9 antikoerper, psmd9 antikoerper, psmd9.L antikoerper, psmD9 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.
Alias Symbols: MGC8644, Rpn4, p27
Protein Interaction Partner: PSMC6, PSMC3, TRIM42, CCDC136, TRIM39, BANP, NCKIPSD, AHCYL1, ELSPBP1, HNRNPA1, CSH1, SHFM1, UBC, TNF, PSMB4, CHUK, TMOD3, PABPC1, TWF2, GNPDA1, XPNPEP1, PYGL, PFKL, P4HB, HNRNPH1, HNRNPF, H2AFZ, AMOTL2, PARK2, BAG3, TNIP2, NUDCD2, DSTN, CPLX1, CD2BP2, UB
Protein Size: 223

Molekulargewicht: 25 kDa

Gen-ID: 5715

NCBI Accession: NM_002813, NP_002804

UniProt: O00233

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway