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Caspase 3 Antikörper (C-Term)

CASP3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Ziege, Meerschweinchen, Schaf, Pferd WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2787903
  • Target Alle Caspase 3 (CASP3) Antikörper anzeigen
    Caspase 3 (CASP3)
    Bindungsspezifität
    • 19
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 12
    • 10
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 281
    • 195
    • 148
    • 30
    • 16
    • 9
    • 9
    • 9
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Ziege, Meerschweinchen, Schaf, Pferd
    Wirt
    • 281
    • 42
    • 4
    • 2
    • 2
    Kaninchen
    Klonalität
    • 273
    • 57
    Polyklonal
    Konjugat
    • 161
    • 27
    • 21
    • 14
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    Dieser Caspase 3 Antikörper ist unkonjugiert
    Applikation
    • 254
    • 109
    • 105
    • 85
    • 79
    • 65
    • 52
    • 36
    • 34
    • 29
    • 28
    • 20
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    NLKYEVRNKN DLTREEIVEL MRDVSKEDHS KRSSFVCVLL SHGEEGIIFG
    Homologie
    Cow: 91%, Dog: 93%, Goat: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CASP3. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CASP3
    Top Product
    Discover our top product CASP3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 277 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Caspase 3 (CASP3)
    Andere Bezeichnung
    CASP3 (CASP3 Produkte)
    Synonyme
    CPP32 antikoerper, CPP32B antikoerper, SCA-1 antikoerper, A830040C14Rik antikoerper, AC-3 antikoerper, Apopain antikoerper, CC3 antikoerper, Caspase-3 antikoerper, Lice antikoerper, Yama antikoerper, mldy antikoerper, xcpp32 antikoerper, casp3 antikoerper, zgc:100890 antikoerper, CASP-3 antikoerper, caspase-3 antikoerper, caspase 3 antikoerper, caspase 3 S homeolog antikoerper, caspase 3, apoptosis-related cysteine peptidase a antikoerper, caspase 3, apoptosis-related cysteine peptidase antikoerper, CASP3 antikoerper, Casp3 antikoerper, casp3.S antikoerper, casp3a antikoerper
    Hintergrund
    CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
    Alias Symbols: CPP32, CPP32B, SCA-1
    Protein Interaction Partner: BAX, PARP1, PTGES3, XIAP, CRYAB, BIRC7, UBC, MDM2, Gzmb, VIM, STAT1, SPTAN1, ROCK1, GSN, DFFA, CASP9, CASP7, CASP6, CASP2, BID, ARHGDIA, TNFSF10, PLA2G4B, CDKN1A, RB1, PRKDC, GLRX, GATA1, SOCS5, YWHAG, MAPK9, MAPK8, SP1, PKN1, CASP8, BIRC3, BIRC2, ZBTB16,
    Protein Size: 277
    Molekulargewicht
    12 kDa
    Gen-ID
    836
    NCBI Accession
    NM_032991, NP_116786
    UniProt
    P42574
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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